Intolerance Screen

What items does this test for?

What's inside the box?

1 x Alcohol wipe
1 x Plaster
1 x Absorbent pad
1 x Five Spot Blood Card
2 x Lancets CE 0344 (pin-prick system)
1 x Return envelope
1 x Activation card with adhesive label

This test uses the IgG4 in your blood sample for intolerance testing, but what does that mean?

IgG and IgE antibodies play an important role in our immune system. The immune system helps our body to fight infections and inflammation caused by external invaders known as antigens like viruses, bacteria, parasitic worms and proteins. We have four classes of IgG antibodies: IgG1, IgG2, IgG3 and IgG4(1). For the INSERT TEST test we are using IgG4 to help us in the identification of those non-immunological responses that can be the cause of common symptoms like: bloating, headaches, stomach pains and diarrhoea.

Why IgG4?

The IgG4 antibodies can influence the inflammatory response but not activate it in. We are using IgG4 in our intolerance tests because we are investigating delayed symptoms that could be associated with food and non-food intolerances (1,2). These do not cause an immediate immunological response, however, could still be causing you problems. For food intolerance, the presence of specific IgE and IgG antibodies can be observed. Some subclasses of IgG (mainly IgG4) inhibit the degranulation of basophils and mast cells and the activation of the complement cascade (2).

At Test Your Intolerance, we use IgG4 exclusively for qualitative intolerance testing. Our tests are not used for the diagnosis of acute or chronic food intolerances; however, we are helping you to draw a map of the reactions that could be the cause of your symptoms. 60% of the world’s population suffers from food intolerance to at least one food antigen. This test is not a quick fix but can help you into your journey to find a better version of yourself. To find out more about the science of IgG4 testing, click here.

References

1. Aalberse RC, Stapel SO, Schuurman J, Rispens T, Immunoglobulin G4: an odd antibody. Clin Exp Allergy. 2009; 39(4): 469-77.
2. Velikova T et al. Methods for detection of food intolerance. RAdvFoodSci: 2018: 1(3): 106-119

What items does this test for?

• Raised IgE values prove clinically significant in identifying IgE-Mediated Allergy.
• Results do not constitute a medical diagnosis on their own, but may be used by your doctor or nutritional therapist to help form a diagnosis or rule out a condition.
• CE approved sample collection kit.
• Quantitative data using an ELISA testing methodology. All values measured in Kilounits per antigen per litre (KUA/L), our scale uses a universal cut off point of 0.35 in classifying a reaction.
• >97% reproducible results.

Important

Blood (ELISA) tests define an intolerance/sensitivity as a specific IgG4 antibody reaction and an allergy as a specific IgE antibody reaction (IgE-Mediated).

All information in the reports produced is intended to support nutritional advice to optimise your diet. The results cannot be used to diagnose, treat or cure medical/health conditions.

The use of antihistamines prior to or during the blood sample collection process may affect your results, please contact our team for further advice.

Always seek the advice of your doctor or other qualified health provider if you have a medical condition and/or medical symptoms. Never disregard professional medical advice or delay in seeking it.